Monitoring and tracking inequality in the services and facilities of urban space justice (Case study: Gorgan city)

Objective: One of the most important factors for sustainable development in the Declaration of Agenda is the twenty-one reduction in urban inequality.Therefore, the necessity of recognizing the current status of the indicators of spatial justice and evaluating urban spaces for any physical, economic, and social planning is desirable in order to des

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Exosomes derived from cancer-associated fibroblasts promote tumorigenesis, metastasis and chemoresistance of colorectal cancer by upregulating circ_0067557 to target Lin28

Abstract Background Cancer Beta Alanine associated fibroblasts (CAFs) can remodel tumor microenvironment by secreting exosomes.This study aimed to investigate the role of exosomes derived from cancer-associated fibroblasts in colorectal cancer (CRC) progression.Methods Circular RNA (circRNA) array was used to identify differentially expressed circR

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PARTICLE, a Triplex-Forming Long ncRNA, Regulates Locus-Specific Methylation in Response to Low-Dose Irradiation

Exposure to low-dose irradiation causes transiently elevated expression of the long ncRNA PARTICLE (gene PARTICLE, promoter of MAT2A-antisense radiation-induced circulating lncRNA).PARTICLE affords both a cytosolic scaffold for the tumor suppressor methionine adenosyltransferase (MAT2A) and a nuclear genetic platform for transcriptional repression.

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